In the knockout phase, teams play against each other over two legs on a home-and-away basis, except for the one-match final. The draw for the round of 16 was held on 16 December 2011. The draws for the quarter-finals, semi-finals and final (to determine the "home" team) will be held on 16 March 2012.
In the draw for the round of 16, the eight group winners were seeded, and the eight group runners-up were unseeded. The seeded teams were drawn against the unseeded teams, with the seeded team hosting the second leg. Teams from the same group or the same association could not be drawn against each other. In the draws for the quarter-finals onwards, there are no seedings, and teams from the same group or the same association may be drawn with each other.
Round of 16
The first legs will be played on 27 and 28 March, and the second legs will be played on 3 and 4 April 2012.
The first legs will be played on 17 and 18 April, and the second legs will be played on 24 and 25 April 2012.
The final will be played on 19 May 2012 at the Allianz Arena in Munich, Germany.